Molecular Diagnosis and Diagnostics

Molecular diagnosis is evolving as a new and eye-opening methodology that merges proteomics and genomics for early detection and diagnosis of cancer. Genomics and proteomics tools are used to detect distinctive molecular signatures like changes in gene expressions, protein biomarker profiles, genetic and epigenetic signatures and other metabolite profile changes. This allows to identify the combinations of biomarkers which may sense the presence or risk of cancer or monitor cancer therapies. sometimes mutations occur in oncogenes, such as KRAS and CTNNB1(β-catenin). Investigating the molecular signature of cancerous cells i.e.  the DNA and its levels of expression via messenger RNA aids physicians to characterize the cancer and to choose the best therapy for their patients